12.12.18_Kids Who Clone: Making the Invisible Visible (Participant)
BioBuilder Learning Lab
700 Main Street
Cambridge, MA 02139
Synthetic biologists create new organisms by modifying the DNA of existing organisms. But since DNA is too small to be seen, how do researchers know that their new organisms will work the way they predict? In this class, we will learn about the DNA sequences that control when information is turned “on” or “off” in bacterial cells. Students will measure bacterial population density using a spectrophotometer, and will perform enzyme assays to determine how changes to DNA control sequences affect gene expression. By the end of class, students will understand how scientists use reporters like B-galactosidase to make the invisible, visible! Lab will end with an exercise in design, using the lab’s tools and concepts to address challenges impacting our world.
Intended Age Group: 10-14 years old
Required background: Some understanding of cells and cell function. A working knowledge about DNA as the coding language of cells. Familiarity with a laboratory environment is helpful but not required.
When registering, please enter the name of the participant as it should appear on a name badge. A separate link is provided for chaperones, who must register but not as a paying attendee. Chaperones may register at http://bit.ly/Dec12Chaperone
A minimum of 10 attendees will be needed to run this workshop. A $35 nonrefundable registration fee covers materials for the workshop for participants. Accompanying chaperones are not charged a fee.
LabCentral does not offer free parking. There is very limited meter parking on Main Street and other adjacent streets. Visitors are encouraged to use the MBTA. LabCentral is a half mile walk directly down Main Street from the Kendall Square/MIT Station on the Red Line and a half mile walk down Mass Ave to Main Street from the Central Square Station on the Red Line.